I-Choline chloride
I-Choline chloride yikhompawundi yendalo enefomyula yekhemikhali i-C5H14ClNO. Yikristale emhlophe ene-hygroscopic, ayinavumba, kwaye inevumba lentlanzi. Iqondo lokunyibilika liyi-305 ℃. Isisombululo samanzi se-10% esine-pH 5-6 asizinzanga kwisisombululo se-alkaline. Le mveliso inyibilika lula emanzini nakwi-ethanol, kodwa hayi kwi-ether, i-petroleum ether, i-benzene, kunye ne-carbon disulfide. Ityhefu ephantsi, i-LD50 (igundane, yomlomo) yi-3400 mg/kg. Isetyenziselwa unyango lwesibindi esinamafutha kunye ne-cirrhosis. Ikwasetyenziswa njengesongezelelo sokondla iinkukhu kunye nemfuyo, inokukhuthaza ama-ovari ukuba avelise amaqanda amaninzi, inkunkuma, kwaye atyebe kwiinkukhu, iintlanzi, kunye nezinye izilwanyana.
Ukusetyenziswa:amayeza, iikhemikhali, iimveliso zokutya, iimveliso zezolimo, izongezo zokutya
Njengesongezelelo sokondla, i-choline chloride ineziphumo ezilandelayo zomzimba:inokuthintela ukuqokelelwa kwamafutha kunye nokuwohloka kwezicubu esibindini nasezintsoni; Inokukhuthaza ukuhlanganiswa kwakhona kwee-amino acids; Inokuphucula izinga lokusetyenziswa kwee-amino acids, ngakumbi i-amino acid methionine ebalulekileyo, emzimbeni. EJapan, i-98% ye-choline chloride isetyenziswa njengesongezelelo sokondla izilwanyana ezifana neenkukhu, iihagu, iinkomo zenyama yenkomo, kunye neentlanzi kunye neeshrimp. Uninzi lwazo lucutshungulwa lube ngumgubo, kwaye indlela yokulungiselela i-50% yomgubo kukongeza kwangaphambili i-particle size excipient efanelekileyo kwi-mixer, uze emva koko ulahle isisombululo samanzi se-choline chloride, esixutywayo nesomileyo. Ezinye iipowders zemveliso zikwadibaniswa neevithamini, iiminerali, amayeza, njl. I-Choline chloride sisiyobisi se-vitamin B esisetyenziselwa izifo ezifana ne-hepatitis, ukuwohloka kwesibindi, i-cirrhosis yasekuqaleni, kunye ne-anemia eyingozi.
I-Choline yinxalenye ebalulekileyo ye-lecithin, edlala indima ebalulekileyo ekugcineni ulwakhiwo oluqhelekileyo kunye nomsebenzi wee-membranes zeseli, kunye ne-lipid metabolism, kwaye inokuthintela ukugcinwa kwamafutha esibindini.
I-Choline ikwayinxalenye ebalulekileyo ekuhlanganisweni kwe-neurotransmitter acetylcholine, kwaye ikwasebenza njengomnikeli we-methyl ekuhlanganisweni kwe-methionine.
I-Choline chloride isetyenziselwa ukukhuthaza ukukhula kunye nokungabikho kwe-choline.
Ukutya kuqulethe inani elithile le-choline, enokuthi yenziwe sisibindi emzimbeni, ngoko ke ngokubanzi ayibangeli ukungabikho kwe-choline. Nangona kunjalo, iinkukhu zeetapile pants, ingakumbi amantshontsho, zifuna kakhulu i-choline kwaye zine-synthesis ephantsi. Ukuba ukutya akufakwanga ngokwaneleyo okanye kondliwa nge-choline encinci (njengombona) ixesha elide, kulula ukubangela ukungabikho.
Xa iinkukhu zasekhaya zigula zizifo zesibindi kwaye zingenawo amanqanaba aneleyo e-vitamin B2 kunye ne-folic acid ekutyeni kwazo, oku kunokubangela ukunqongophala kwe-choline. Xa ukunqongophala kwe-choline kwenzeka, iihagu zibonisa ukukhula okucothayo, ukuqina kwamalungu kunye ne-dyskinesia, ukugcwala kwamafutha esibindi, kunye nokusebenza okunciphileyo kokuzala. Iinkukhu zibonisa ukukhula okucothayo, i-tibia emfutshane netyebileyo, enokuqhekeka kwemisipha, isifo sesibindi esinamafutha, kunye nokuncipha kwemveliso yamaqanda.
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